Variations are differences in traits or characteristics among individuals of a species. These differences can be observed in various aspects, including physical features (such as height, colouration, or shape), physiological traits (like blood type), and genetic makeup. Variations can occur in both sexually and asexually reproducing organisms.
Heredity refers to the process by which traits, characteristics, and genetic information are passed from one generation to the next in living organisms, including humans. It is a fundamental biological concept that explains how offspring inherit traits and features from their parents.
Mendelian genetics, also known as Mendelism or classical genetics, is a fundamental concept in the field of genetics that was developed by Gregor Mendel, an Austrian scientist, in the mid-19th century. Mendelian genetics is the study of how traits are inherited from one generation to the next and how the principles of inheritance operate. Mendel's work with pea plants laid the foundation for our understanding of genetic inheritance.
Before delving into Mendelian genetics, it's essential to understand some key genetic and biological terms. These terms provide the foundational knowledge necessary for comprehending Mendel's experiments and the principles of inheritance. Here are some important terms to know:
Gregor Mendel, born in 1822, was a monk in the Augustinian monastery in Brno, Austria (now in the Czech Republic). Intrigued by the variation he observed in garden peas (Pisum sativum), Mendel decided to systematically investigate how traits were passed from one generation to the next. He chose peas because they were easy to cultivate, had easily distinguishable traits, and could be controlled in breeding experiments.
Mendel's experiments, conducted over several years in the 1860s, involved careful and meticulous cross-breeding of pea plants with specific traits.
Key Aspects of Mendel’s Work:
Mendel carefully documented these results, and from his experiments, he formulated two fundamental principles of heredity.
Mendel's Laws of Inheritance are fundamental principles that describe how genes are passed from one generation to the next.
Mendel's Law of Dominance is one of the fundamental principles of genetics. This law explains how different alleles (variants of a gene) interact to determine an organism's phenotype (observable traits). It is best illustrated through Mendel's experiments with pea plants, particularly in the context of plant height, where he observed dominant and recessive traits.
Expression of Traits
Example using Tall (T) and Dwarf (t) Pea Plants
F1 Generation:
Genotype: Tt (heterozygous)
Phenotype: All tall plants
When the F1 tall plants (Tt) are allowed to self-pollinate and produce the second generation (F2), Mendel observed a 3:1 ratio of tall to dwarf plants in the offspring.
F2 Generation:
Genotype: TT, Tt (tall), tt (dwarf)
Phenotype: 3 tall plants (TT and Tt) to 1 dwarf plant (tt)
This observation confirms Mendel's Law of Dominance, as the dominant allele (T) and the tall phenotype are prevalent in the F1 generation, but the recessive allele (t) and the dwarf phenotype reappear in the F2 generation in a predictable Mendelian ratio.
Mendel's Law of Segregation explains how alleles, which are different forms of a gene, are separated and passed onto offspring during the formation of gametes (sperm and egg cells). The Law of Segregation is based on Mendel's experiments with pea plants and is a crucial component of classical genetics.
Key points of Mendel's Law of Segregation:
Mendel's Pea Plant Example
Mendel's experiments with pea plants involved studying traits like flower colour, seed shape, and plant height.
F1 Generation:
Genotype: Pp
Phenotype: All purple flowers
Mendel allowed the F1 generation (Pp) plants to self-pollinate.
In the second generation (F2), he observed a 3:1 ratio of purple to white flowers.
F2 Generation:
Genotype: PP, Pp (purple), pp (white)
Phenotype: 3 purple flowers (PP and Pp) to 1 white flower (pp)
In the F1 generation, the alleles for flower colour (P and p) segregate during the formation of gametes.
Each F1 plant produces two types of gametes: one carrying the P allele and one carrying the p allele.
When the F1 plants self-pollinate, the gametes combine randomly during fertilisation, resulting in the 3:1 phenotypic ratio observed in the F2 generation.
The Law of Independent Assortment is one of Gregor Mendel's fundamental principles of inheritance, and it describes how genes for different traits segregate, or assort, independently of each other during the formation of gametes (sperm and egg cells). This law applies when considering the inheritance of multiple genes or traits simultaneously and is particularly relevant when genes are located on different chromosomes.
The Law of Independent Assortment states that genes located on different chromosomes segregate independently of each other during gamete formation. In other words, the inheritance of one trait is not dependent on the inheritance of another trait.
Key Points of the Law of Independent Assortment:
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Mendel's Pea Plant Example:
In this experiment, Mendel studied two pairs of traits: seed shape (round or wrinkled) and seed colour (yellow or green).
F1 Generation for Seed Shape:
Genotype: Rr (heterozygous for seed shape)
Phenotype: All round seeds
In the second pair of traits, seed colour (yellow or green), he observed that yellow seeds (dominant) were produced in the F1 generation. No green seeds (recessive) were observed.
F1 Generation for Seed Colour:
Genotype: Yy (heterozygous for seed colour)
Phenotype: All yellow seeds
Mendel allowed the F1 generation (RrYy) plants to self-pollinate.
In the F2 generation, Mendel observed a 9:3:3:1 phenotypic ratio for the combined traits of seed shape and colour. This ratio consisted of round yellow seeds, round green seeds, wrinkled yellow seeds, and wrinkled green seeds.
F2 Generation for Seed Shape and Color:
Genotypes: RRYY, RRYy, RrYY, RrYy, RRyy, Rryy, rrYY, rrYy, rryy
Phenotypes: 9 round yellow seeds, 3 round green seeds, 3 wrinkled yellow seeds, 1 wrinkled green seed
Mendel's experiments with dihybrid crosses revealed that the traits for seed shape and seed colour were inherited independently. The inheritance of seed shape did not influence the inheritance of seed colour and vice versa.
The 9:3:3:1 phenotypic ratio in the F2 generation showed that the two pairs of traits (seed shape and colour) assorted independently during gamete formation.
This law illustrates that genes located on different chromosomes segregate independently into gametes, contributing to genetic diversity in offspring.
Genes as Information Source: Within cells, DNA serves as the information source for creating proteins. A specific segment of DNA responsible for instructing the production of a particular protein is called a gene.
Gene Control of Traits:
Contributions of Both Parents: Based on the interpretations of Mendelian experiments, both parents must contribute equally to the DNA of their offspring during sexual reproduction. To achieve this, each pea plant, for instance, must possess two sets of genes, one inherited from each parent.
Role of Germ Cells: Germ cells are specialised cells involved in sexual reproduction. They must have only one set of genes, despite most other cells in the body containing two sets. This single-set mechanism is crucial for ensuring that traits can be independently inherited from both parents.
Chromosomes and Independent Inheritance: Genes are not present as single long threads of DNA but are located on separate, independent pieces called chromosomes. Each cell contains two copies of each chromosome, one from the mother and one from the father. When germ cells combine during fertilisation, they restore the normal number of chromosomes in the offspring. This mechanism guarantees the stability of the species' DNA and explains the results of Mendel's experiments on inheritance.
Blood groups are inherited according to Mendelian genetics, and the key factors in this inheritance are the genes responsible for blood group antigens.
Sex determination is the biological process by which an organism's sex, whether it will develop into a male or female, is decided. The mechanisms of sex determination can vary among different species. Here's an explanation of sex determination in various organisms, including humans:
Genetic Sex Determination (Humans):
Environmental Sex Determination (Reptiles and Others):
In some species, such as reptiles, the temperature at which fertilised eggs are incubated can determine the sex of the offspring.
For example, in certain turtles, higher incubation temperatures may result in female offspring, while lower temperatures produce males.
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Evolution is described as a sequence of gradual changes that occur in primitive organisms over an extended period, resulting in the emergence of new species. The term "evolution" is derived from the Latin word "evolvere," meaning to unroll or unfold.
All the plants and animals we see today have evolved from ancestors that lived on Earth in the distant past. Evolution is responsible for the variety of life forms that currently exist.
Evolution is often summarised by the phrase "descent with modification." This means that as populations of organisms reproduce over generations, they accumulate changes or modifications in their genetic material (DNA). These modifications can be caused by various mechanisms, including mutations (random changes in DNA) and genetic recombination.
Acquired Traits
Inherited Traits
Charles Darwin's Theory of Evolution, often referred to as the Theory of Natural Selection, is a groundbreaking scientific explanation for how species change and adapt over time. Darwin introduced this theory in his influential book "On the Origin of Species," published in 1859.
Key Aspects of Darwin's Theory of Evolution:
Speciation is the process by which one or more new species arise from an existing species. It is a fundamental concept in biology and evolution that explains the origin of Earth's diverse array of life forms. Speciation occurs through a series of genetic, ecological, and reproductive changes that ultimately result in populations becoming distinct and reproductively isolated from one another.
Key Aspects of Speciation:
It's important to note that speciation is not an instantaneous event but rather a gradual process that occurs over many generations. Additionally, there are various modes of speciation, including allopatric speciation (resulting from geographical isolation) and sympatric speciation (arising within the same geographical area), each with its own set of mechanisms.
Overall, speciation is a key driver of biodiversity on Earth and helps explain the vast variety of life forms that exist today.
Evidence for evolution comes from various fields of science, including biology, palaeontology, and genetics. These pieces of evidence collectively support the theory that species on Earth have changed and diversified over time. Here are some key pieces of evidence for evolution:
Fossil Record
Homologous Structures
Analogous Structures
While these vegetables look significantly different from their wild cabbage ancestor, they share a common evolutionary origin through artificial selection by farmers.
In summary, the evolution of complex structures and the diversification of organisms can occur through gradual changes, intermediate stages, and the selective pressures of the environment. Artificial selection, as demonstrated with the wild cabbage example, further emphasises the role of selective breeding in shaping the diversity of life forms.
Evolution should not be equated with progress for several reasons. Evolution is about adaptation to diverse environments, and it can lead to a wide range of outcomes, including both simpler and more complex organisms. It is not a linear march towards perfection but a dynamic and context-dependent phenomenon that has shaped the diversity of life on Earth.
The study of human evolution has employed various tools and techniques, including excavation, time-dating, fossil analysis, and DNA sequencing. Here are some key points regarding human evolution based on the provided information:
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1. How does DNA play a role in heredity?
DNA, also known as deoxyribonucleic acid, is the genetic material that codes for an organism's characteristics. It is inherited from the parents, and individual differences in the DNA sequence add to the variety of characteristics.
2. What is genetic variation, and why is it important in evolution?
The variety of genes and alleles within a population is referred to as genetic variation. Because it gives natural selection the raw material to work with and enables species to adapt to changing surroundings, it is essential to evolution.
3. What is genetic variation?
The diversity of genes and alleles within a population is referred to as genetic variation. It is essential to evolution because it gives natural selection the raw material to work with, enabling organisms to adapt to shifting environmental conditions.
4. What is evolution, and how does it relate to heredity?
Evolution is the slow process by which organisms evolve. Since qualities are inherited and can change over future generations due to the transfer of genetic material, heredity is essential to evolution.
5. Are acquired traits inherited?
A person's lifetime acquired qualities are typically not transferred to their progeny. The primary mechanism of heredity is not learned qualities, but rather the transmission of genetic information recorded in DNA.
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